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pentobarbital will lower the extent or effect of ripretinib by impacting hepatic/intestinal enzyme CYP3A4 metabolism.pentobarbital will reduce the extent or impact of buprenorphine buccal by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.pentobarbital will lower the extent or impact of meloxicam by influencing hepatic en